Author

Kipp W. Johnson

Mount Sinai Health SystemORCID 0000-0002-5102-741XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Benjamin Scott GlicksbergiD· 4 shared Joel T. DudleyiD· 4 shared Khader ShameeriD· 3 shared Ben ReadheadiD· 2 shared Amjesh RevikumariD· 1 shared Claire McCallumiD· 1 shared Eli Rappaport· 1 shared Jamie S. Hirsch· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersBioinformatics

Benjamin Scott GlicksbergORCID

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Author profile →

4 papers

Recent·Most cited

Pleiotropic Variability Score: A Genome Interpretation Metric to Quantify Phenomic Associations of Genomic Variants

Khader Shameer, Benjamin Scott Glicksberg, Marcus A. Badgeley, Kipp W. Johnson, Joel T. Dudley

The paper introduces the Pleiotropic Variability Score (PVS) to quantify the phenomic associations of genomic variants using semantic reasoning and validates it with electronic health records.

bioRxiv · Jul 18, 2021 · PreprintBioinformatics

fragilityindex: An R Package for Statistical Fragility Estimates in Biomedicine

Kipp W. Johnson, Eli Rappaport, Khader Shameer, Benjamin Scott Glicksberg, Joel T. Dudley

The paper introduces an R package for calculating fragility index in clinical trials and extends the method to survival analysis and logistic regression.

bioRxiv · Feb 27, 2019 · PreprintBioinformatics

Prioritizing Small Molecule as Candidates for Drug Repositioning using Machine Learning

Khader Shameer, Kipp W. Johnson, Benjamin Scott Glicksberg, Rachel A. Hodos, Ben Readhead, Max Tomlinson, Joel T. Dudley

This study uses machine learning to prioritize small molecules for drug repositioning by analyzing chemical properties and leveraging public drug databases.

bioRxiv · Jun 4, 2018 · PreprintBioinformatics

Rapid Therapeutic Recommendations in the Context of a Global Public Health Crisis using Translational Bioinformatics Approaches: A proof-of-concept study using Nipah Virus Infection

Khader Shameer, Kipp W. Johnson, Ben Readhead, Benjamin S. Glicksberg, Claire McCallum, Amjesh Revikumar, Jamie S. Hirsch, Kevin Bock, John Chelico, Negin Hajizadeh, Michael Oppenheim, Joel T. Dudley

This study uses computational drug repositioning and gene expression analysis to identify potential therapies for Nipah Virus infection.

bioRxiv · Jun 4, 2018 · PreprintMicrobiology