Carsten Krieg

MIMIC: a flexible pipeline to register and summarize IMC-MSI experiments

MIMIC is a pipeline that integrates Mass Spectrometry Imaging and Imaging Mass Cytometry to analyze spatial omics data, recovering known molecular associations and revealing novel spatial relationships.

Resolving sialylated N Glycans and immune cell landscapes using a unified same-section IMC-MSI workflow

This study compares two workflows for integrating imaging mass cytometry (IMC) and sialic-acid-linkage-resolving N-glycan MALDI-MSI on the same tissue section, finding that IMC-first acquisition preserves antibody signal and glycan integrity.

Spatially-smoothed quantification improves cell typing in imaging mass cytometry datasets

The paper improves cell typing in imaging mass cytometry by addressing spillover through spatial smoothing and marker aggregation techniques.