Chilakamarti V. Ramana

Insights into functional connectivity in mammalian signal transduction pathways by pairwise comparison of protein interaction partners of critical signaling hubs

The paper identifies critical nodes in immune signaling pathways by analyzing shared interaction partners of transcription factors using PIC-VENN.

Regulation of Lysosome-Associated Membrane Protein 3 (LAMP3) in Lung Epithelial Cells by Coronaviruses (SARS-CoV-1/2) and Type I Interferon Signaling

This study investigates how SARS-CoV-1/2 and type I interferon signaling regulate LAMP3 expression in lung epithelial cells and its potential role in innate immunity.

Lung Epithelial Regulation of BCL2 Related Protein A1 (BCL2A1) by Coronaviruses (SARS-CoV) and Type I Interferon Signaling

This study investigates how SARS-CoV-2 and type I interferon signaling regulate BCL2A1 expression in human lung epithelial cells and identifies associated gene regulatory changes.

Regulation of early growth response-1 (Egr-1) gene expression by Stat1-independent type I interferon signaling and respiratory viruses

This study shows that Egr-1 is induced by IFN-β, TLR ligands, and respiratory viruses independently of the Stat1 pathway and is involved in antiviral response and inflammation.

Profiling transcription factor sub-networks in type I interferon signaling and in response to SARS-CoV-2 infection

The paper profiles transcription factor sub-networks in type I interferon signaling and SARS-CoV-2 infection to identify differential regulation in immune and lung cells.