Author

Francesca Massenzio

King's College LondonORCID 0000-0002-5189-7546Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Jemeen SreedharaniD· 1 shared Matthew A. WhiteiD· 1 shared Michael P. ColemaniD· 1 shared Sami J. BarmadaiD· 1 shared Xingli LiiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperNeuroscience

Jemeen SreedharanORCID

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1 paper

Recent·Most cited

Inhibiting glycogen synthase kinase 3 suppresses TDP-43-mediated neurotoxicity in a caspase-dependant manner

Matthew A. White, Francesca Massenzio, Xingli Li, Michael P. Coleman, Sami J. Barmada, Jemeen Sreedharan

This study shows that inhibiting GSK3 reduces TDP-43 levels and neurotoxicity in mammalian neurons by promoting TDP-43 turnover through a caspase-dependent mechanism.

bioRxiv · Feb 3, 2021 · PreprintNeuroscience