Cancer BiologyFrontiers in ImmunologyPeer-reviewed
Tracing the stemness and malignant transition in a heritable colorectal cancer Lynch Syndrome by single-cell RNA-seq analysis
Junfeng Xu, Jianlin Zhang, Yuhang Li…·Zhigang Cai
This paper uses single-cell RNA sequencing to analyze cellular changes in Lynch Syndrome colorectal cancer, identifying cancer stem cells, immune infiltration, and mutation burden during malignant transition.