Identification of the Molecular Basis of Anti-fibrotic Effects of Soluble Guanylate Cyclase Activator Using the Human Lung Fibroblast Phosphoproteome
Sunhwa Kim, Ashmita Saigal, Weilong Zhao, Peyvand Amini, Alex M. Tamburino, Subharekha Raghavan, Maarten Hoek
This study identifies phosphorylation changes in human lung fibroblasts induced by an sGC activator, revealing potential molecular mechanisms of its anti-fibrotic effects.
bioRxiv · Jun 12, 2020 · PreprintMolecular Biology