Author

Iwona J. Fijałkowska

Institute of Biochemistry and Biophysics, Polish Academy of SciencesORCID 0000-0002-5307-4332Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alina KrasiliaiD· 2 shared Deepali ChaudhryiD· 2 shared Michał DmowskiiD· 2 shared Malgorzata JedrychowskaiD· 1 shared Milena Denkiewicz-KrukiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersCancer Biology

Alina KrasiliaORCID

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2 papers

Recent·Most cited

Pan-cancer multi-omics analysis identifies non-canonical oncogenic functions beyond DNA replication of the POLE2 subunit of DNA Polymerase epsilon

Alina Krasilia, Deepali Chaudhry, Iwona J. Fijałkowska, Michał Dmowski

This study identifies POLE2 as a contributor to genome stability, a cancer biomarker, and therapeutic target through pan-cancer multi-omics analysis.

bioRxiv · Dec 12, 2025 · PreprintCancer Biology

The effects of CDC45 mutations on DNA replication and genome stability

Milena Denkiewicz-Kruk, Deepali Chaudhry, Alina Krasilia, Malgorzata Jedrychowska, Iwona J. Fijałkowska, Michał Dmowski

This study examines how CDC45 mutations affect DNA replication and genome stability, finding defects in replication initiation and increased mutation rates.

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · Mar 24, 2025Peer-reviewedGenetics