Author

Mattia Buratto

University of FerraraORCID 0000-0002-5359-6464Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Francesca SalvatoriiD· 1 shared Mariaconcetta SicurellaiD· 1 shared Mariangela PappadàiD· 1 shared Peggy MarconiiD· 1 shared Valentina SimioniiD· 1 shared Valeria TugnoliiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperNeuroscience

Francesca SalvatoriORCID

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1 paper

Recent·Most cited

CRISPR/Cas9-based silencing of the ATXN1 gene in Spinocerebellar ataxia type 1 (SCA1) fibroblasts

Francesca Salvatori, Mariangela Pappadà, Mariaconcetta Sicurella, Mattia Buratto, Valentina Simioni, Valeria Tugnoli, Peggy Marconi

This study validates CRISPR/Cas9 as a therapeutic strategy for SCA1 by downregulating ATXN1 expression in patient fibroblasts with minimal off-target effects.

bioRxiv · Jul 4, 2020 · PreprintNeuroscience