Integrative Transcriptomic and Network Analysis Reveals Small Open Reading Frames as Regulators of DNA Methylation-Linked Pathogenicity and Adaptability in Leptospira interrogans
ChungYuen Khew, Nur Syafiqah Mohd Fowzi, Nurul Najihah Zaifulzaman, Sarahani Harun, Shairah Abdul Razak, Zeti‐Azura Mohamed‐Hussein, Norfarhan Mohd‐Assaad
The paper identifies sORFs in Leptospira interrogans that link DNA methylation to pathogenicity and adaptability through transcriptomic and network analysis.
bioRxiv · Dec 11, 2025 · PreprintBioinformatics