Integrating CSF and EV Proteomes Enhances Biomarker Discovery by Capturing Shared Variation Across Compartments
Bianca R. P. Brown, Xiaoting Li, Monica R. Grasty, Andrew D. Miranker, Gamze Gürsoy
The paper integrates CSF and EV proteomes to enhance biomarker discovery by capturing shared variation across compartments, improving biological concordance and identifying more candidates in a smaller cohort.
bioRxiv · Oct 2, 2026 · PreprintSystems Biology