Visualizing Deep Mutational Scan Data
C. K. Sruthi, Hemalatha Balaram, Meher K. Prakash
This paper visualizes deep mutational scan data for TEM-1 β-lactamase to better understand mutation effects through attribute analysis.
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Jawaharlal Nehru Centre for Advanced Scientific ResearchORCID 0000-0002-5476-3359Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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C. K. Sruthi, Hemalatha Balaram, Meher K. Prakash
This paper visualizes deep mutational scan data for TEM-1 β-lactamase to better understand mutation effects through attribute analysis.
C. K. Sruthi, Meher K. Prakash
The paper analyzes amino acid co-evolution in viral genomes to classify viral complexity using network characteristics and finds distinct patterns in different viruses.
C. K. Sruthi, Meher K. Prakash
The paper introduces a model that predicts phenotypic outcomes of protein mutations using sequence and structural data, improving prediction accuracy with random mutations over systematic substitutions.
Soutick Saha, C. K. Sruthi, Meher K. Prakash
The paper develops a microsimulation model to quantify how chemotaxis affects nutrient uptake and bacterial population growth, finding significant benefits only under nutrient-rich conditions.