The paper assesses tau pathology in cognitively normal older adults using PET imaging and links it to age, sex, race, amyloid status, and cognitive decline.

65 citationstop 3%

humanimaging

𝕏 PostBluesky

NeuroscienceJournal of Nuclear MedicinePeer-reviewedMay 4, 2018

First in-human PET study of 3 novel tau radiopharmaceuticals: RO6958948

Dean Foster Wong, Robert A. Comley, Hiroto Kuwabara…·Edilio Borroni

This paper reports the first human PET study of three novel tau radiopharmaceuticals, finding that [18F]RO-948 shows superior characteristics for tau pathology characterization in Alzheimer's disease.

104 citationstop 1%

humanimaging

𝕏 PostBluesky

NeuroscienceThe International Journal of NeuropsychopharmacologyPeer-reviewedMar 5, 2018

PET Brain imaging of α7-nAChR with ASEM: Reproducibility, occupancy, receptor density, and changes in schizophrenia

Dean Foster Wong, Hiroto Kuwabara, Andrew G. Horti…·ALBERT H. GJEDDE

This study uses PET imaging with [18F]ASEM to assess reproducibility, occupancy, receptor density, and changes in a7-nAChR in schizophrenia patients.

65 citations

humanimaging

𝕏 PostBluesky