Dean Foster Wong

Differential sphingosine-1-phosphate receptor-1 protein expression in the dorsolateral prefrontal cortex between schizophrenia Type 1 and Type 2

The paper compares S1PR1 protein expression in schizophrenia subtypes using postmortem brain tissue and suggests its potential as an in vivo PET biomarker.

Transcranial photoacoustic imaging of NMDA-evoked focal circuit dynamics in rat hippocampus

The paper validates the focal specificity of transcranial functional photoacoustic voltage-sensitive dye imaging in rat hippocampus by correlating NMDA-evoked neural activity with glutamate release and EEG signals.

Tau pathology in cognitively normal older adults

The paper assesses tau pathology in cognitively normal older adults using PET imaging and links it to age, sex, race, amyloid status, and cognitive decline.

Transcranial recording of electrophysiological neural activity in the rodent brain in vivo using functional photoacoustic imaging of near-infrared voltage-sensitive dye

This paper demonstrates the use of functional photoacoustic imaging with a near-infrared voltage-sensitive dye to record in vivo neural activity in rats without craniotomy, showing distinguishable responses in seizure models.

First in-human PET study of 3 novel tau radiopharmaceuticals: RO6958948

This paper reports the first human PET study of three novel tau radiopharmaceuticals, finding that [18F]RO-948 shows superior characteristics for tau pathology characterization in Alzheimer's disease.

PET Brain imaging of α7-nAChR with ASEM: Reproducibility, occupancy, receptor density, and changes in schizophrenia

This study uses PET imaging with [18F]ASEM to assess reproducibility, occupancy, receptor density, and changes in a7-nAChR in schizophrenia patients.