Co-substrate pools can constrain and regulate pathway fluxes in cell metabolism
Robert West, Hadrien Delattre, Εlad Noor, Elisenda Feliu, Orkun S. Soyer
The paper develops a mathematical framework to show co-substrate cycling imposes flux limits in metabolic pathways and demonstrates this using simulations and existing metabolic data.
eLife · Feb 17, 2023Peer-reviewedSystems Biology