Synthetic BiologyACS Sustainable Chemistry & EngineeringPeer-reviewed
Elucidation and engineering of arabinofuranosyltransferase to enable total de novo biosynthesis of paris saponins in yeast
Haowen Wang, Yi Yang, Ziya Wu…·Xianan Zhang
This paper reports the first complete de novo biosynthesis of four bioactive Paris saponins in yeast by engineering sugar donor specificity and integrating biosynthetic modules.
DOI 10.1021/acssuschemeng.6c06083