Cancer BiologybioRxivPreprint
Loss of ESE3/EHF is sufficient to promote cell plasticity, transformation and androgen-independent status in the early stage of prostate carcinogenesis.
Domenico Albino, Giada Sandrini, Carola Musumeci…·Giuseppina Maria Carbone
This study shows that loss of EHF promotes cell plasticity, transformation, and androgen independence in early prostate cancer by disrupting lineage integrity and activating downstream pathways.