Author

Mark Aspinall-O’Dea

Charles River Laboratories (United Kingdom)ORCID 0000-0002-5526-974XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Abhilash BarpandaiD· 1 shared Amrik S. KangiD· 1 shared Anupam Anand OjhaiD· 1 shared Arun P. WiitaiD· 1 shared Benjamin J. HuangiD· 1 shared Beth Walker· 1 shared Caitlin E. CornelliD· 1 shared Clare Adams· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Abhilash BarpandaORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintSep 10, 2026

Deep Learning-based Modeling Enhances Efficacy of Natural Ligand CAR Binders Targeting CD70

Amrik S. Kang, Radhika Dalal, Mingcheng Li…·Arun P. Wiita

This study uses deep learning and physics-based modeling to engineer a CD27 variant that improves the efficacy of CD70-targeting CAR T-cells across multiple cancer models.

DOI 10.64898/2026.09.06.749651

humanproteomics

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