Implementation of a multiplex PCR amplfication system combined with next-generation genome sequencing to decipher the circulation of Human coronavirus 229E lineages in Southern France
Houmadi Hikmat, Justine Py, Céline Boschi, Emilie Burel, Lorlane Le Targa, Matthieu Million, Lucile Lesage, Aurélie Morand, Bernard La Scola, Philippe Colson
The paper describes the implementation of a multiplex PCR system combined with next-generation sequencing to analyze HCoV-229E genomes from Southern France, identifying a new lineage and sublineages.
bioRxiv · Mar 12, 2025 · PreprintMicrobiology