Author

Yashaswi Shrestha

Broad InstituteORCID 0000-0002-5567-0277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Jesse S. BoehmiD· 2 shared Alireza Kashani· 1 shared Anne Elizabeth CarpenteriD· 1 shared Atanas Kamburov· 1 shared Eejung Kim· 1 shared Elizabeth Worstell· 1 shared Gad Getz· 1 shared Heiko HorniD· 1 shared

Activity by Year

2015-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersSystems Biology

Jesse S. BoehmORCID

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2 papers

Recent·Most cited

Systems BiologyeLifePeer-reviewedMar 18, 2017

Systematic morphological profiling of human gene and allele function reveals Hippo-NF-κB pathway connectivity

Mohammad Hossein Rohban, Shantanu Singh, Xiaoyun Wu…·Anne Elizabeth Carpenter

The paper uses morphological profiling to identify gene function and connectivity, revealing TRAF2/C-REL's negative regulation of Hippo pathway effectors.

165 citationstop 2%

humanimaging

Cancer BiologybioRxivPreprintAug 25, 2015

A comparative analysis of network mutation burdens across 21 tumor types augments discovery from cancer genomes

Heiko Horn, Michael S. Lawrence, Jessica Xin Hu…·Kasper Lage

The paper quantifies network mutation burdens across 21 tumor types to identify putative cancer genes, finding 62 new candidates with greater sensitivity for low-frequency mutations.

DOI 10.1101/025445

humanwhole-genome sequencing