Author

Alain G. Nicolas

Centre National de la Recherche ScientifiqueORCID 0000-0002-5606-7808Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 3 Organism:yeast· 3 Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Gianni LitiiD· 3 shared Simone MozzachiodiiD· 3 shared Lorenzo TattiniiD· 2 shared Melania D’AngioloiD· 2 shared Sophie LoeilletiD· 2 shared Agnès LlorediD· 1 shared Agurtzane IrizariD· 1 shared Angela Lutazi· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Gianni LitiORCID

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3 papers

Recent·Most cited

GeneticsNature CommunicationsPeer-reviewedMay 11, 2022

Unlocking the functional potential of polyploid yeasts

Simone Mozzachiodi, Kristoffer Krogerus, Brian R. Gibson…·Gianni Liti

The paper introduces a method to improve industrial yeast strains through recombination during mitotic growth, identifying clones with enhanced biotechnological traits.

21 citations

yeastwhole-genome sequencing

GeneticsbioRxivPreprintDec 4, 2020

Aborting meiosis overcomes hybrid sterility

Simone Mozzachiodi, Lorenzo Tattini, Agnès Llored…·Gianni Liti

Aborting meiosis followed by return-to-growth promotes genome-wide recombination in sterile yeast hybrids, enabling adaptation and genetic mapping.

4 citations

yeastDNA methylation

GenomicsMolecular Biology and EvolutionPeer-reviewedJul 30, 2019

Accurate tracking of the mutational landscape of diploid hybrid genomes

Lorenzo Tattini, Nicolò Tellini, Simone Mozzachiodi…·Gianni Liti

The paper introduces MuLoYDH, a method to accurately track mutations in yeast diploid hybrids, revealing genetic background effects and loss-of-heterozygosity patterns.

56 citationstop 3%

yeastwhole-genome sequencing