Author

Ashwil Klein

University of the Western CapeORCID 0000-0002-5606-886XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Adeola Raji· 1 shared Adewale Oluwaseun FadakaiD· 1 shared Ameerah-Imaan AbrahamsiD· 1 shared Arun GokuliD· 1 shared Augustine Innalegwu DanieliD· 1 shared D. HolmaniD· 1 shared David AdelekeiD· 1 shared Enriquay SmithiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Adeola Raji

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2 papers

Recent·Most cited

BioinformaticsTranslational OncologyPeer-reviewedFeb 3, 2026

AlphaMissense pathogenicity scores predict response to immunotherapy and enhances the predictive capability of tumor mutation burden

David Adeleke, Adewale Oluwaseun Fadaka, Nicole Remaliah Samantha Sibuyi…·Rick J. Jansen

The paper introduces AlphaTMB, a composite biomarker combining tumor mutation burden with pathogenicity scores, showing improved survival prediction in immunotherapy response.

DOI 10.1016/j.tranon.2026.102697

humanwhole-exome sequencing

𝕏 PostBluesky

MicrobiologybioRxivPreprintDec 18, 2025

Pantoea in agriculture: Balancing promise and pathogenicity

D. Holman, Enriquay Smith, Adeola Raji…·Marshall Keyster

The paper discusses the dual role of Pantoea species as both beneficial biofertilizers and potential plant pathogens, highlighting the need for careful regulation in agricultural use.

DOI 10.64898/2025.12.18.695097

𝕏 PostBluesky