Author

Nila Palaniappan

Washington University in St. LouisORCID 0000-0002-5641-2894Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Evan M. LeeiD· 2 shared Fumihiko UranoiD· 2 shared Megha VermaiD· 2 shared Abby F. Tang· 1 shared Bess Adkins MarshalliD· 1 shared CRIS M. BROWN· 1 shared Emiko M. Pope· 1 shared Kasra A. Vand· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Evan M. LeeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genotype-Based Severity Scoring System in Wolfram Syndrome: Correlation with Onset of Cardinal Symptoms and WFS1 Gene Variant Types

Liam Oiknine, Abby F. Tang, Evan M. Lee, Nila Palaniappan, Megha Verma, Kasra A. Vand, Sahiti Somalraju, Sarath Chandra Janga, Fumihiko Urano

Higher WFS1 genotype scores (variant frame, transmembrane location) tracked earlier diabetes mellitus and optic atrophy onset in 324 Wolfram patients, not hearing loss or diabetes insipidus.

Frontiers in Genetics · Jul 14, 2026Peer-reviewedGenetic & Genomic Medicine✦ In-depth digest

Genotype and Clinical Characteristics of Patients with Wolfram Syndrome and WFS1-related Disorders

Evan M. Lee, Megha Verma, Nila Palaniappan, Emiko M. Pope, Sammie Lee, Lindsey Blacher, Pooja Neerumalla, William An, Toko Campbell, CRIS M. BROWN, Stacy Hurst, Bess Adkins Marshall, Tamara G. Hershey, Virginia Nunes, Miguel López de Heredia, Fumihiko Urano

This study investigates the genotype-phenotype relationship in Wolfram syndrome, finding that specific WFS1 gene variants correlate with earlier onset and more severe disease manifestations.

Frontiers in Genetics · Jun 21, 2023Peer-reviewedGenetic & Genomic Medicine