Author

Elizabeth R. Vanderwall

Seattle Children's Research InstituteORCID 0000-0002-5684-3694Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Jason S. DebleyiD· 4 shared Lucille M. RichiD· 4 shared Basilin BensoniD· 3 shared Matthew C. AltmaniD· 3 shared Nyssa Becker SamanasiD· 3 shared Patricia C. dela CruziD· 3 shared Steven F. ZiegleriD· 3 shared Teal S. HallstrandiD· 3 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCell Biology

Jason S. DebleyORCID

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4 papers

Recent·Most cited

Cell BiologyAmerican Journal of Respiratory Cell and Molecular BiologyPeer-reviewedMar 25, 2026

Viral replication and interferon responses in bronchial epithelia is enhanced by Th17 cells

Weston T. Powell, Tomasz Janczyk, Patricia C. dela Cruz…·Jason S. Debley

This study shows Th17 cells enhance interferon responses and viral replication in bronchial epithelial cells from asthmatic children infected with rhinovirus-16.

DOI 10.1093/ajrcmb/aanag070

humanbulk RNA-seq

Cell BiologyAmerican Journal of Respiratory Cell and Molecular BiologyPeer-reviewedMar 6, 2026

Infants who develop BPD have an airway endotype defined by vimentin expression and ciliary loss

Laurie C. Eldredge, Yan Han, Gail H. Deutsch…·Jason S. Debley

The paper develops an ex vivo model of BPD using airway epithelial cells and identifies a molecular endotype characterized by vimentin expression and ciliary loss in infants with BPD.

DOI 10.1093/ajrcmb/aanag044

humanbulk RNA-seq

Cell BiologybioRxivPreprintDec 8, 2025

IL-13 Modulates Antiviral Effector and Proinflammatory Pathways in Rhinovirus-Infected Pediatric Bronchial Epithelium

Patricia C. dela Cruz, Basilin Benson, Naresh Doni Jayavelu…·Jason S. Debley

This study shows IL-13 suppresses antiviral defenses and enhances proinflammatory pathways in RV-infected bronchial epithelium, contributing to asthma exacerbations.

1 citation

humanbulk RNA-seq

Cell BiologybioRxivPreprintOct 19, 2025

Transcriptomic Profiling of Bronchial Epithelium Reveals Dysregulated Interferon and Inflammatory Responses to Rhinovirus in Exacerbation-Prone Pediatric Asthma

Naresh Doni Jayavelu, Basilin Benson, Patricia C. dela Cruz…·Jason S. Debley

This study identifies dysregulated interferon and inflammatory responses to rhinovirus in exacerbation-prone pediatric asthma using transcriptomics and protein analysis.

DOI 10.1101/2025.10.19.683298

humanbulk RNA-seq