Unveiling novel conserved HIV-1 open reading frames encoding T cell antigens using ribosome profiling.
Lisa Bertrand, Annika Nelde, Bertha Cecilia Ramírez, Isabelle Hatin, Hugo Arbès, Pauline François, Stéphane Demais, Emmanuel Labaronne, Didier Décimo, Laura Guiguettaz, Sylvie Grégoire, Anne Bet, Guillaume Beauclair, Antoine Gross, Maja C. Ziegler, , Arnaud Moris
This study uses ribosome profiling to identify conserved HIV-1 alternative open reading frames (ARFs) that encode T cell antigens, revealing new targets for vaccination.
Nature Communications · Feb 18, 2025Peer-reviewedImmunology