Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer’s disease
Qiongshi Lu, Ryan L. Powles, Sarah B. Abdallah, Derek Ou, Qian Wang, Yiming Hu, Yisi Lu, Wei Liu, Boyang Li, Shubhabrata Mukherjee, Paul K. Crane, Hongyu Zhao
The paper introduces GenoSkyline-Plus, a framework for tissue-specific functional annotation of the human genome, showing its utility in identifying immune-related DNA elements linked to late-onset Alzheimer’s disease.
PLoS Genetics · Jul 24, 2017Peer-reviewedGenetics