Author

Duncan Kirby

University of TorontoORCID 0000-0002-5819-2629Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

Anton ZilmaniD· 2 shared Boian S. AlexandroviD· 1 shared Dvira SegaliD· 1 shared Matthew GerryiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiophysics

Anton ZilmanORCID

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2 papers

Recent·Most cited

BiophysicsPhysical review. EPeer-reviewedFeb 20, 2025

Ligand induced receptor multimerization achieves the specificity enhancement of kinetic proofreading without associated costs

Duncan Kirby, Anton Zilman

This study shows that ligand-induced receptor multimerization enhances specificity like kinetic proofreading without energy costs or signal loss.

3 citations

mechanistic / dynamical model

𝕏 PostBluesky

BiophysicsPLoS Computational BiologyPeer-reviewedJan 27, 2025

Specificity and tunability of efflux pumps: a new role for the proton gradient?

Matthew Gerry, Duncan Kirby, Boian S. Alexandrov…·Anton Zilman

This study shows that efflux pump specificity is influenced by proton gradient and membrane potential, offering new strategies to combat bacterial resistance.

4 citations

statistical model

𝕏 PostBluesky