Zhuoyang Chen

A comprehensive benchmarking study of protein structure alignment tools based on downstream task performance

This study benchmarks nine protein structure alignment tools across homology detection, phylogeny reconstruction, and function inference, showing structure-based methods often outperform sequence-based ones.

DualNetGO: A Dual Network Model for Protein Function Prediction via Effective Feature Selection

DualNetGO selects features from PPI networks and protein attributes to predict protein functions, improving Fmax scores across Gene Ontology categories in human and mouse datasets.