Martin J. Holland

This study compares transcriptomic responses of human conjunctival epithelial cells and macrophages to ocular Chlamydia trachomatis genovars A and B, revealing strain-specific and cell-type differences in gene expression over time.

This study analyzes genomic variation in Chlamydia trachomatis serovars A and B from Gambian trachoma-endemic villages to understand strain diversification and evolutionary pressures.

The paper analyzes genomic variation in Chlamydia trachomatis from Ethiopia to assess its role in continued transmission after SAFE interventions.

The paper identifies genetic pathways associated with Chlamydia trachomatis serological response and finds overlap in pathway associations between ocular and urogenital infections.

The paper analyzes Ct genomic diversity and identifies SNPs associated with ocular localization and disease severity in a West African trachoma-endemic population.

This paper evaluates a commercial real-time PCR assay for detecting Chlamydia trachomatis in ocular swabs, finding good sensitivity but lower specificity compared to other tests.