Author

Andrzej Ożyhar

Wrocław University of Science and TechnologyORCID 0000-0002-5874-784XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Aneta TarczewskaiD· 2 shared Barbara P. KlepkaiD· 2 shared Beata Greb‐MarkiewicziD· 2 shared Nikola SozańskaiD· 2 shared Anna Niedźwiecka-KornaśiD· 1 shared Lilia Zukowa· 1 shared Michał DadleziD· 1 shared Niedźwiecka Anna· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Aneta TarczewskaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Intrinsically disordered bHLH family member TCF4 drives LLPS in a DNA-dependent manner

Nikola Sozańska, Barbara P. Klepka, Anna Niedźwiecka-Kornaś, Beata Greb‐Markiewicz, Andrzej Ożyhar, Aneta Tarczewska

This study shows TCF4 undergoes LLPS in vitro, which is reversible and regulated by DNA binding, suggesting a role in transcriptional activation and potential involvement in neurological diseases.

bioRxiv · Jun 18, 2025 · PreprintBiochemistry

The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor

Nikola Sozańska, Barbara P. Klepka, Niedźwiecka Anna, Lilia Zukowa, Michał Dadlez, Beata Greb‐Markiewicz, Andrzej Ożyhar, Aneta Tarczewska

This study characterizes the molecular structure of TCF4, revealing it as a large intrinsically disordered protein with a stable bHLH domain and disordered regions that may mediate gene regulation.

bioRxiv · Feb 6, 2025 · PreprintMolecular Biology