Author

Aamir Saifuddin

Imperial College LondonORCID 0000-0002-5888-5556Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Dezső MódosiD· 2 shared John P. ThomasiD· 2 shared Nick PowelliD· 2 shared Tamas Douglas KorcsmarosiD· 2 shared Balázs BoháriD· 1 shared Diana ComaniD· 1 shared Diana PappiD· 1 shared Domenico CozzettoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersSystems Biology

Dezső MódosORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintAug 12, 2026

A dysregulated stromal remodelling programme characterises prior anti-TNF failure in ulcerative colitis

John P. Thomas, Tyler Wooldridge, Domenico Cozzetto…·Nick Powell

The paper identifies a stromal remodelling programme in ulcerative colitis patients who failed prior anti-TNF therapy, linking it to MAPK/EGFR signalling and suggesting MEK/EGFR inhibitors as potential treatments.

DOI 10.64898/2026.08.11.744139

humanbulk RNA-seq

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Systems BiologyScience SignalingPeer-reviewedFeb 3, 2026

Decoding Cytokine Networks in Ulcerative Colitis to Identify Pathogenic Mechanisms and Therapeutic Targets

Marton L. Olbei, Isabelle Hautefort, John P. Thomas…·Tamas Douglas Korcsmaros

The paper maps cytokine interaction networks in ulcerative colitis to uncover novel pathogenic mechanisms and therapeutic targets.

9 citationstop 1%

humanscRNA-seq

𝕏 PostBluesky