Author
Imperial College LondonORCID 0009-0000-7326-7556Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
John P. Thomas, Sherine Hermangild Kottoor, Jonathan W. Lo…·Nick Powell
This paper identifies a microbiota-responsive polyfunctional cytotoxic CD4⁺ T-cell state linked to mucosal inflammation and treatment resistance in ulcerative colitis.
John P. Thomas, Tyler Wooldridge, Domenico Cozzetto…·Nick Powell
The paper identifies a stromal remodelling programme in ulcerative colitis patients who failed prior anti-TNF therapy, linking it to MAPK/EGFR signalling and suggesting MEK/EGFR inhibitors as potential treatments.
Brock Wooldridge, Chloé Orland, Erik D. Enbody…·Beth Shapiro
The paper analyzes the genomes of black abalone to assess genetic impacts of a population collapse and finds no spatial genetic structure, high genetic diversity, and low WS prevalence, suggesting translocation could aid recovery.