A simple approximation to bias in gene-environment interaction estimates when a case might not be the case
Iryna V. Lobach, Inyoung Kim, Alexander V. Alekseyenko, Siarhei Lobach, Li Zhang
The paper derives a simple approximation to bias in gene-environment interaction estimates when clinically diagnosed cases may include a nuisance pathologic state, and demonstrates its validity through simulations and an Alzheimer's disease study.
Frontiers in Genetics · Oct 9, 2019Peer-reviewedGenetics