Author
Belarusian State University
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Ying Sheng, Chiung‐Yu Huang, Siarhei Lobach, Lydia B. Zablotska, Iryna V. Lobach, for the Alzheimer’s Disease Neuroimaging Initiative
The paper assesses bias in genetic effect estimates when a continuous variable is omitted from logistic regression models in case-control studies and proposes methods to recover this bias.
Genetic Epidemiology · Jan 20, 2020Peer-reviewedGenetics
Iryna V. Lobach, Ying Sheng, Siarhei Lobach, Lydia B. Zablotska, Chiung‐Yu Huang
The paper compares case-control and case-only estimates for gene-environment interactions in the presence of misclassified clinical diagnoses, using simulations and an Alzheimer's disease study.
Genetic Epidemiology · Oct 30, 2019Peer-reviewedGenetics
Iryna V. Lobach, Inyoung Kim, Alexander V. Alekseyenko, Siarhei Lobach, Li Zhang
The paper derives a simple approximation to bias in gene-environment interaction estimates when clinically diagnosed cases may include a nuisance pathologic state, and demonstrates its validity through simulations and an Alzheimer's disease study.
Frontiers in Genetics · Oct 9, 2019Peer-reviewedGenetics
Iryna V. Lobach, Inyoung Kim, Alexander V. Alekseyenko, Siarhei Lobach, Li Zhang
The paper derives a simple approximation to correct genetic effect estimates in case-control GWAS when multiple disease states share a clinical diagnosis and applies it to Alzheimer's disease.
Genetic Epidemiology · Mar 19, 2019Peer-reviewedGenetics
Iryna V. Lobach, Joshua Neil Sampson, Siarhei Lobach, Alexander V. Alekseyenko, Alexandra Piryatinska, Tao He, Li Zhang
The paper derives a theoretical approximation for bias in gene-environment interaction estimates in case-control studies with silent disease and validates it through simulations and a prostate cancer study.
Genetic Epidemiology · Jan 8, 2019Peer-reviewedGenetics