A polygenic predictor of treatment-resistant depression using whole exome sequencing and genome-wide genotyping
Chiara Fabbri, Siegfried Kasper, Alexander Kautzky, Joseph Zohar, Daniel Souery, Stuart Montgomery, Diego Albani, Gianluigi Forloni, Panagiotis P. Ferentinos, Dan Rujescu, Julien Mendlewicz, Rudolf Uher, Cathryn M. Lewis, Alessandro Serretti
The paper develops a polygenic predictor for treatment-resistant depression using whole exome sequencing and genome-wide genotyping, finding that genetic scores combined with clinical factors improve prediction.
Translational Psychiatry · Feb 3, 2020Peer-reviewedGenetic & Genomic Medicine