Author

Elizabeth A. Fedak

University of UtahORCID 0000-0002-6030-8328Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

Frederick R. AdleriD· 2 shared Lisa M. AbeggleniD· 2 shared Erin L. Young· 1 shared Joshua D. Schiffman· 1 shared Joshua David SchiffmaniD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersSystems Biology

Frederick R. AdlerORCID

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2 papers

Recent·Most cited

What p53 sees: ATM and ATR activation through crosstalk between DNA damage response pathways

Elizabeth A. Fedak, Frederick R. Adler, Lisa M. Abegglen, Joshua David Schiffman

The paper constructs a mathematical model of ATM and ATR crosstalk in response to DNA damage, showing how crosstalk mechanisms influence pro-apoptotic signaling.

Bulletin of Mathematical Biology · Mar 11, 2021Peer-reviewedSystems Biology

Dynamics of the p53 response to ionizing and ultraviolet radiation

Elizabeth A. Fedak, Frederick R. Adler, Erin L. Young, Lisa M. Abegglen, Joshua D. Schiffman

This paper proposes a mathematical model explaining how p53 exhibits distinct dynamic responses to ionizing and ultraviolet radiation, with implications for cell fate decisions.

bioRxiv · Jul 12, 2018 · PreprintCancer Biology