BioinformaticsMoleculesPeer-reviewed
CRFalign: A Sequence-structure alignment of proteins based on a combinationof HMM-HMM comparison and conditional random fields
Sung Jong Lee, Keehyoung Joo, Sangjin Sim…·Jooyoung Lee
CRFalign improves protein sequence-structure alignment by combining HMM-HMM comparison with conditional random fields and gradient boosted trees, showing better performance on remote homologs.