Author

Carlos Castilla

Universidad de NavarraORCID 0000-0002-6087-3140Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Ángel RubioiD· 1 shared Edurne San José‐EneriziD· 1 shared Estíbaliz MirandaiD· 1 shared Felipe PrósperiD· 1 shared Fernando CarazoiD· 1 shared Leire Gárate· 1 shared Marian GimenoiD· 1 shared Xabier AgirreiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperGenomics

Ángel RubioORCID

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1 paper

Recent·Most cited

Identifying Lethal Dependencies with HUGE Predictive Power from Large-Scale Functional Genomic Screens

Fernando Carazo, Edurne San José‐Eneriz, Marian Gimeno, Leire Gárate, Estíbaliz Miranda, Carlos Castilla, Xabier Agirre, Ángel Rubio, Felipe Prósper

The paper improves prediction of lethal gene dependencies using the HUGE method, achieving 75x higher statistical power than existing methods in cancer genomics.

bioRxiv · Oct 29, 2021 · PreprintGenomics