Systems BiologybioRxivPreprint
A quantitative network modeling approach to evaluate the role of cytokine combinations on CD4+ T cell differentiation, partial polarization, and plasticity
Mariana Esther Martínez-Sánchez, Leonor Huerta, Elena R Alvarez-Buylla, Carlos Villarreal
The paper extends a Boolean network model of CD4+ T cell differentiation to a continuous model to assess how cytokine concentrations and combinations influence differentiation and plasticity.
DOI 10.1101/232884