Author

Laurent Ludwig

Johns Hopkins UniversityORCID 0000-0002-6121-7196Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Assay:protein sequence· 1 Research Focus:sequence-to-function modeling· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

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Jeffrey J. GrayiD· 1 shared Michael ChungyouniD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Jeffrey J. GrayORCID

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1 paper

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BioinformaticsbioRxivPreprintJun 11, 2026

GermRL: Alleviating The Germline Bias In Autoregressive Antibody Language Models Through Reinforcement Learning

Laurent Ludwig, Michael Chungyoun, Jeffrey J. Gray

This paper introduces GermRL, a reinforcement learning framework that reduces germline bias in antibody language models, improving mutation diversity while maintaining structural plausibility.

DOI 10.64898/2026.06.08.730660

protein sequencedeep learning

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