BioinformaticsBulletin of Mathematical BiologyPeer-reviewed
Eco-Evolutionary Dynamics of Proliferation Heterogeneity: A Phenotype-Structured Model for Tumor Growth and Treatment Response
Lara Schmalenstroer, Haojun Chen, Russell C. Rockne, Farnoush Farahpour
This paper develops a phenotype-structured model to study how proliferation heterogeneity affects tumor growth and treatment response, showing that optimal proliferation rates shift with tumor size and treatment regimes.
DOI 10.1007/s11538-026-01740-1