Yihang Shen

AutoTuneX improves transcript assembly accuracy by predicting optimal parameters for RNA-seq samples.

DTMol is a diffusion model for pocket-based molecular docking that outperforms existing methods on benchmark datasets and identifies new JAK2 inhibitors.

The paper introduces a novel algorithm to improve Hi-C contact matrices by inferring linear genomes from Hi-C data using genome graphs, resulting in more accurate structural representations.

The paper introduces a probabilistic method to correct a previously uncharacterized Hi-C artifact caused by incorrect alignment in repeat regions.

The paper uses topological data analysis to study chromosome structure changes during cellular differentiation across three cell lines, identifying global and local topological differences.