The paper develops a kinetic model of A{beta} accumulation in Tg2576 mice to evaluate therapeutic interventions and highlights the role of feedback cycles in disease progression.

2 citations

mousestatistical model

𝕏 PostBluesky

Systems BiologyThe Journal of Physical Chemistry BPeer-reviewedDec 13, 2018

Kinetic Model of Translational Autoregulation

Vivian Tyng, Michael E. Kellman

The paper analyzes a kinetic model of translational autoregulation, showing that negative feedback improves control efficiency and response speed.

5 citations

statistical model

𝕏 PostBluesky