GeneticsGenome ResearchPeer-reviewed
Gene by environment interaction mouse model reveals a functional role for 5-hydroxymethylcytosine in neurodevelopmental disorders
Ligia Assumpção Papale, Andy Madrid, Qi Zhang…·Reid S. Alisch
The paper shows that prenatal stress in Cntnap2 heterozygous mice disrupts 5hmC levels and alters gene expression, leading to neurodevelopmental behaviors similar to knockout mice.
18 citations