Author

Hua Min Shen

Baylor College of MedicineORCID 0000-0002-6250-9377Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:whole-genome sequencing· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Fritz Joachim SedlazeckiD· 2 shared Ginger MetcalfiD· 2 shared Kavya KottapalliiD· 2 shared Qingchang MengiD· 2 shared Richard A. GibbsiD· 2 shared Sejal Salvi· 2 shared Sravya Venkata BhamidipatiiD· 2 shared Vipin K. MenoniD· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenomics

Fritz Joachim SedlazeckORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of tight junction protein claudin 18 uncovers alveolar epithelial stem cell plasticity and emergence of non-fibrogenic transitional progenitors

Alessandra Castaldi, J. Chin, B Ma, Max W. Chang, K. Samimi, A. Allen, W Pinson-Rose, Jonathan Castillo, Peyman Zamani, M Xie, Nataly Arias, Kayvon Solaimanpour, Y Liu, Hua Min Shen, BT Scott, , Zea Borok

The paper identifies regeneration-associated transitional progenitors (RATPs) in Cldn18 knockout mice, showing they are less fibrogenic and contribute to lung repair rather than fibrosis.

bioRxiv · Oct 1, 2025 · PreprintCell Biology

Structural variation across 138,134 samples in the TOPMed consortium

Goo Jun, Adam C. English, Ginger Metcalf, Jianzhi Yang, Mark Chaisson, Nathan Pankratz, Vipin K. Menon, William J. Salerno, Olga A. Krasheninina, Albert V. Smith, John Lane, Tom W. Blackwell, Hyun Min Kang, Sejal Salvi, Qingchang Meng, , Fritz Joachim Sedlazeck

The paper presents a comprehensive catalog of structural variants across 138,134 individuals, identifying novel variants and their associations with cardio-metabolic and hematologic traits.

bioRxiv · Jan 25, 2023 · PreprintGenomics

Fully resolved assembly of Cryptosporidium parvum

Vipin K. Menon, Pablo C. Okhuysen, Cynthia L. Chappell, Medhat Mahmoud, Medhat Mahmoud, Qingchang Meng, HarshaVardhan Doddapaneni, Vanesa Vee, Yi Han, Sejal Salvi, Sravya Venkata Bhamidipati, Kavya Kottapalli, George Weissenberger, Hua Min Shen, Matthew Clayton Ross, , Fritz Joachim Sedlazeck

The paper presents a high-quality, complete reference genome for Cryptosporidium parvum using Oxford Nanopore and Illumina reads, enabling comprehensive genomic studies.

GigaScience · Jan 1, 2022Peer-reviewedGenomics