BioinformaticsCell DiscoveryPeer-reviewed
A synergistic generative-ranking framework for tailored design of therapeutic single-domain antibodies
Yu Kong, Jiale Shi, Fandi Wu…·Tianlei Ying
This paper introduces TFDesign-sdAb, a deep learning framework for designing therapeutic single-domain antibodies with tailored functionalities, achieving high success rates in generating Protein A-binding sdAbs.
2 citations