Bone marrow-derived CCR5-expressing macrophages promote venous thrombus resolution by up-regulating plasminogen activators and VEGF
Mizuho Nosaka, Yuko Ishida, Yumi Kuninaka, Akiko Ishigami, Akihiko Kimura, Akira Taruya, Atsushi Tanaka, Naofumi Mukaida, Toshikazu Kondo
This study shows that CCR5-expressing macrophages in venous thrombi promote resolution by increasing VEGF and plasminogen activators, and that CCR5 deficiency impairs thrombus resolution.
bioRxiv · Sep 18, 2023 · PreprintMolecular Biology