A membrane-targeted photoswitch restores physiological ON/OFF responses to light in the degenerate retina
Gaia Ziraldo, Sara Cupini, Valentina Sesti, Emanuela Delfino, Guglielmo Lanzani, Chiara Bertarelli, Fabio Benfenati, Stefano Di Marco
This paper demonstrates that Ziapin2, a membrane photoswitch, restores ON/OFF visual responses in degenerate retinas by modulating neuronal excitability and conductances.
Nature Communications · Jan 11, 2025Peer-reviewedNeuroscience