Cancer BiologyNature CommunicationsPeer-reviewed
Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically "actionable" signalling axis in triple negative breast cancer
Xue Yang, Xiuquan Ma, Tianyue Zhao…·Roger J. Daly
This study identifies a novel feed-forward signalling axis between PEAK1 and CAMK2 in TNBC, showing that targeting CAMK2 can inhibit PEAK1-driven oncogenic processes.
10 citations