Atomistic simulation study reveals transduction of mechanical work generated by ATP hydrolysis onto myosin II functional loops
Ikuo Kurisaki, Hideo Higuchi, Shigenori Tanaka, Madoka Suzuki
This paper uses atomistic simulations to show that ATP hydrolysis in myosin II stores mechanical energy in functional loops through hydrogen bond rearrangements, independent of heat release.
bioRxiv · Jan 23, 2026 · PreprintBiophysics