Shigenori Tanaka

This paper uses atomistic simulations to show that ATP hydrolysis in myosin II stores mechanical energy in functional loops through hydrogen bond rearrangements, independent of heat release.

This study uses coarse-grained simulations to show ribosomal proteins stabilize tRNA in the ribosome, with positively charged residues in their C-terminal regions playing a key role.

This paper introduces a diffusion-based generative model for end-to-end protein-ligand complex structure generation without relying on existing protein structures.